In a nutshell, we showed that over-the-counter cheap generic antibiotic neomycin can be repurposed in nasal formulation to prevent & treat infection, block transmission, and reduce disease burden against a wide array of viruses. Since this is a host-directed strategy and virus-agnostic, it holds promise as a prophylactic strategy against any viral threat.
The advice in the screencapped thread was to apply a little with a q-tip to the inside of the nostrils.
There is no info on any dangers of doing this very often, but if you can’t avoid a high-risk environment it’s worth trying.
Here’s a thread about the study. https://threadreaderapp.com/thread/1782535781338222960.html
here’s the study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5918160/
A concern I have about this is the long term effect on the nasal microbiome. In the same way that using antibiotics orally can fuck up your gut microbiome and lead to an increased risk of other health problems, could fucking up the nasal microbiome lead to poorer viral resistance in the long term, or an increased chance of developing allergy/histamine/MCAS issues (which are already triggered by COVID infections)?
The authors share your concerns
Our results demonstrate a surprising and broad antiviral effect of the aminoglycoside family of antibiotics, when applied to mucosal surfaces. However, we do not advocate for use of these compounds as antivirals, as aminoglycoside application is expected to cause local dysbiosis of commensal bacterial community.
Hmm I have used either that stuff or petroleum jelly in my nose in the winter at peak flu times because the cold winter air gives me nosebleeds and it’s a good remedy for a dry sinus. Perhaps I reaped another benefit without knowing.
I’m flying on Sunday, so I’ll give this a try.
Seems to me like actual anti-virals like iota-carrageenan (Betadine brand) nasal spray would be more effective…
The incidence of COVID-19 differs significantly between subjects receiving the nasal spray with I-C (2 of 196 [1.0%]) and those receiving placebo (10 of 198 [5.0%]). Relative risk reduction: 79.8% (95% CI 5.3 to 95.4; p=0.03). Absolute risk reduction: 4% (95% CI 0.6 to 7.4).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8493111/
Iota-Carrageenan patients reported a mean blocked nose score of 0.42, corresponding to a reduction of approximately 50% (Figure 3). Further post hoc analysis of this symptom revealed that 71.4% of Iota-Carrageenan patients did not report the symptom blocked nose at the end of the study. In the placebo group only 36.4% of subjects were free of this symptom.
[…]
viral load in the placebo group increased almost 6- fold (579%), while it dramatically decreased by 92% in the Iota-Carrageenan group (p < 0.009).
Every flight huh? Watch the feds start putting the bioweapon in the ice and biscoff cookies now that we’re onto them.
